Internship - Metabolic Behavior in Plasmid Production

We are currently searching for an enthusiastic intern to study metabolic pathways in plasmid production, within the Advanced Therapies API Process Development department, part of Johnson & Johnson Innovative Medicine in Leiden. This team consists of ~25 employees with background(s) in bioprocess design, biochemistry and molecular biology.

We are looking for a proactive individual whom is looking to develop their skills in problem solving, experimental/analytical data and building hands on experience with offline analytics.

• • Master student in biotechnology, bioprocess development, biochemistry, or a similar study
• • Affinity with metabolic analysis for bioreactor cell cultivation
• • You are available for a minimum of 6 months and 40 hours per week
• • Fluent in English, both verbally and in writing
• Ability to work independently as well as part of a multidisciplinary team
• Flexibility to adapt to changing business and project needs

A thorough understanding of cellular metabolism forms the basis for designing robust and scalable upstream biotechnological processes. Metabolic analysis explains cellular responses to varying process conditions. By understanding the interplay between the formation of (by)products and the physiological state of the cells, a forward control strategy can be designed for real-time bioreactor process control.

This internship focuses on using existing online process and analytical data, together with metabolite analysis of archived samples. These data sets can be used to:

• Get a deeper understanding of the interplay between bioreactor process conditions, formation of (by)products and product quality.
• Convert measured information into actionable insights that facilitate improved bioprocess development and outcomes.
• Develop predictive models in which (already available) spectra are coupled to analytes, with the goal to further develop a process analytical tool for real-time monitoring.

The Advanced Therapies API (Active Pharmaceutical Ingredient) Process Development department designs and develops scalable manufacturing processes for a diverse panel of pharmaceutical products. Our work spans the full workflow from cell culture through downstream purification. We partner closely with our local pilot plant, to enable production of innovative therapies for clinical evaluation.
J&J is a global healthcare company dedicated to bringing meaningful innovation to health. Our business focuses on the discovery, development, manufacture, and marketing of medical technologies and pharmaceuticals. In our organization, entrepreneurial people thrive in a dynamic culture where innovation and J&J mindset are central.

• The famous J&J Credo, we prioritize our patients, customers, and employees;
• We invest in your professional development, offering ample training and opportunities to grow both your technical skills and leadership abilities;
• A modern environment that's professional yet informal. Easily connect and exchange ideas with senior colleagues;
• Join an environment where your unique perspective is welcomed. We believe diverse voices drive better innovation.

Good to know: you will receive a WhatsApp message from us within 15 minutes of submitting your application. We will ask you a few short questions about your application to help you faster. Don't have WhatsApp? No problem! We will contact you by phone or email.

Recruitment J&J

Waldo Kriel

Question? Feel free to contact us!

This is how applying for a job is done via Randstad. Find out how we can help you find a job.